Serum aldosterone as a predictor of heart rhythm disorders in acute myocardial infarction

Nerma Resić, Mirza Dilić, Azra Durak-Nalbantić, Alen Džubur, Enisa Hodžić, Nina Hadžibegić, Marina Vučijak-Grgurević, Edin Begić

Abstract


Introduction: In addition to the fastest reperfusion procedure

of coronary arteries blood flow, identification of patients with
increased risk of early and late complications is of the utmost
importance in acute myocardial infarction (AMI).
Methods: We included total of 207 patients in the acute phase
of myocardial infarction, which were divided into two groups,
127 patients without clinical symptoms of heart failure (HF)
and 60 patients with HF symptoms. For all patients serum aldosterone
levels were determined 24 hours after acute MI.
Results: In the group of decompensated patients, changes in
aldosterone level did not show a statistically significant effect
on paroxysmal supraventricular tachycardia (PSVT) occurrence
(p > 0.05), while in the group of compensated patients there is
statistically significant effect on PSVT occurrence (p =0.004).
Changes in aldosterone level in the group of decompensated
(p=0,030) and compensated patients (p=0,024), showed statistically
significant influence on the ventricular tachycardia (VT)
occurrence. In the group of compensated patients, changes in
aldosterone level showed a statistically significant effect on ventricular
fibrillation (VF) occurrence (p = 0.024).
Conclusion: Plasma aldosterone level in patients with acute
myocardial infarction has a significant influence on the occurrence
of cardiac rhythm disorders irrespective of the existence of
cardiac decompensation.
Keywords: aldosterone, myocardial infarction, prediction.


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